# TCDB Superfamily	MAG.T13.29	MAG.C2.12	MAG.T11.11	MAG.T11.14	MAG.T11.1	MAG.T11.56	MAG.T11.57	MAG.T11.59	MAG.T12.26	MAG.T11.24	MAG.T11.25	MAG.T11.72	MAG.T13.20	MAG.T11.77	MAG.T12.46	MAG.T12.69	MAG.T13.57	MAG.T13.59	MAG.T13.71	MAG.T13.60	MAG.T13.85	MAG.T13.90	MAG.T21.70	MAG.T22.48	MAG.T23.20	MAG.T13.83	MAG.T21.30	MAG.T21.39	MAG.T22.36	MAG.T22.49	MAG.T23.24	MAG.T23.60	MAG.T23.71
AAA-ATPase Superfamily	1.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	1.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	1.0	1.0	0.0	0.0	0.0	0.0
ABC1, ABC2, ABC3 Superfamilies	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	1.0	0.0	0.0	0.0	0.0
APC Superfamily	6.0	1.0	0.0	3.0	0.0	5.0	0.0	0.0	1.0	0.0	0.0	0.0	1.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	1.0	0.0	1.0	0.0	1.0	1.0	0.0	0.0	0.0
ATP-dependent Clp Protease (Clp) Superfamily	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0
Ankyrin Repeat Domain-containing (Ank) Superfamily	4.0	1.0	1.0	0.0	1.0	12.0	2.0	1.0	4.0	4.0	1.0	2.0	2.0	0.0	1.0	3.0	0.0	1.0	1.0	1.0	1.0	4.0	1.0	3.0	2.0	1.0	1.0	4.0	2.0	1.0	5.0	2.0	2.0
ArsA ATPase (ArsA) Superfamily	15.0	3.0	2.0	20.0	0.0	38.0	1.0	3.0	3.0	2.0	0.0	4.0	1.0	3.0	1.0	2.0	5.0	0.0	1.0	0.0	2.0	13.0	4.0	9.0	61.0	0.0	3.0	7.0	6.0	2.0	4.0	3.0	0.0
ArsB Membrane Protein (ArsB) Superfamily	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Azolectin-Cytochrome c Pore-forming (ACCP) Superfamily	6.0	0.0	0.0	2.0	0.0	4.0	0.0	0.0	4.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	2.0	4.0	0.0	0.0	4.0	2.0	0.0	0.0	1.0	0.0
BMC Shell Protein Superfamily	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0
Bacterial Bacteriocin (BB) Superfamily	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0
CAAX Superfamily	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
CPA Superfamily	3.0	1.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	1.0	1.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	1.0	1.0	0.0	1.0	0.0	1.0	2.0	0.0	0.0	0.0
Calmodulin/Calcineurin/KChIP (CaCa) Superfamily	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cation Diffusion Facilitator  (CDF) Superfamily	0.0	0.0	0.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Copper Resistance (CuR) Superfamily	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0
Drug/Metabolite Transporter (DMT) Superfamily	2.0	0.0	1.0	2.0	0.0	0.0	1.0	0.0	0.0	1.0	1.0	0.0	0.0	1.0	1.0	1.0	2.0	0.0	1.0	0.0	1.0	1.0	2.0	0.0	2.0	0.0	1.0	1.0	1.0	1.0	2.0	0.0	0.0
ENaC/P2X Superfamily	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
GTPase, Type 1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Glycosyl Transferase/Transporter (GTT) Superfamily	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Glycosyl/Acyl Transferase (GAT) Superfamily	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Heavy Metal Binding Domain	1.0	3.0	2.0	8.0	0.0	4.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	1.0	0.0	1.0	1.0	1.0	1.0	2.0	0.0	1.0	1.0	0.0	2.0	2.0	0.0	0.0	2.0	0.0	2.0	1.0	0.0
Holin III Superfamily	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Holin IV Superfamily	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hydrolase Superfamily	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0
IT Superfamily	6.0	1.0	0.0	1.0	0.0	1.0	1.0	1.0	2.0	0.0	1.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	2.0	3.0	1.0	0.0	3.0	1.0	1.0	0.0	1.0	0.0
Iron-Sulfur Protein (ISP) Superfamily	6.0	5.0	2.0	6.0	2.0	4.0	2.0	2.0	1.0	2.0	2.0	3.0	2.0	2.0	2.0	0.0	2.0	2.0	2.0	3.0	2.0	1.0	0.0	2.0	3.0	1.0	2.0	5.0	4.0	2.0	0.0	0.0	0.0
LysE Superfamily	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0
Major Facilitator (MFS) Superfamily	3.0	0.0	1.0	2.0	0.0	7.0	0.0	2.0	1.0	1.0	1.0	1.0	1.0	1.0	0.0	1.0	1.0	1.0	1.0	0.0	0.0	1.0	2.0	3.0	3.0	0.0	0.0	1.0	3.0	1.0	0.0	0.0	3.0
Major Intrinsic Protein (MIP) Superfamily	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	1.0	1.0	0.0	1.0	0.0	0.0	0.0	1.0	1.0	0.0	1.0	0.0	1.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0
Multidrug Resistance Protein, Na+ Transporting Mrp (Mrp) Superfamily	4.0	5.0	0.0	9.0	0.0	1.0	0.0	0.0	10.0	2.0	0.0	1.0	0.0	7.0	0.0	1.0	0.0	0.0	1.0	2.0	0.0	1.0	3.0	3.0	11.0	0.0	0.0	5.0	3.0	0.0	0.0	0.0	1.0
Multidrug/Oligosaccharidyl-lipid/Polysaccharide Flippase (MOP) Superfamily	1.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
MusI (MusI) Superfamily	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Outer Membrane Pore-forming Protein I (OMPP-I) Superfamily	1.0	1.0	0.0	0.0	0.0	4.0	0.0	1.0	1.0	0.0	2.0	1.0	0.0	0.0	0.0	1.0	2.0	2.0	0.0	1.0	1.0	0.0	7.0	2.0	0.0	1.0	0.0	0.0	1.0	5.0	0.0	0.0	0.0
Outer Membrane Pore-forming Protein II (OMPP-II) Superfamily	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
PTS-GFL Superfamily	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Protein Kinase (PK) Superfamily	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
RTX-toxin Superfamily	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Resistance-Nodulation-Cell Division (RND) Superfamily	5.0	2.0	0.0	3.0	0.0	5.0	1.0	0.0	2.0	4.0	0.0	2.0	0.0	0.0	0.0	1.0	1.0	0.0	0.0	1.0	0.0	0.0	3.0	1.0	1.0	1.0	0.0	2.0	4.0	0.0	0.0	0.0	0.0
Stomatin/Erlin/Podicin Superfamily	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0
Tetraspan Junctional Complex Protein or MARVEL (4JC) Superfamily	1.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0
Transmembrane One Electron Transfer Cytochrome (TM-Cyt) Superfamily	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Transporter-Opsin-G protein-coupled receptor (TOG) Superfamily	1.0	0.0	0.0	0.0	1.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	1.0	0.0	1.0	2.0	0.0
Urea Transporter/Na+ Exporter (UT/RnfD/NqrB) Superfamily	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	2.0	0.0	0.0
VIC Superfamily	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.0	0.0	2.0	0.0	0.0	0.0	1.0	1.0	0.0	0.0	1.0	0.0	0.0	1.0	1.0	0.0	0.0	0.0	2.0	0.0	0.0	3.0	1.0	1.0
Vesicle-associated Membrane Protein (VAMP) Superfamily	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
YIP Superfamily	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	1.0	0.0	1.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	1.0	1.0	1.0	1.0	0.0	0.0	0.0	0.0